Kidney patients may face heart damage from toxic particles

A study published in Circulation reports that diseased kidneys release tiny particles reported to be toxic to the heart, and researchers described molecular signals linking the two organs.

Researchers reported a study in the peer‑reviewed journal Circulation that found diseased kidneys released tiny particles reported to be toxic to the heart. The authors described these particles as carrying molecular signals that connect the kidney and the heart. Uta Erdbrügger, an associate professor at the University of Virginia School of Medicine, is quoted about investigating interorgan communication. Susmita Sahoo, an associate professor at the Icahn School of Medicine at Mount Sinai, is listed as the study's senior author. Key findings: - The study in Circulation reported that diseased kidneys released tiny particles that were reported to be toxic to the heart. - The authors described molecular communication between the kidney and the heart as a possible link between the organs. - The paper names Uta Erdbrügger (University of Virginia) and Susmita Sahoo (Mount Sinai) among its authors. Summary: The report presents a possible mechanism connecting kidney disease and heart disease via small particles carrying molecular signals. The finding was published in Circulation and was presented by the study authors as a step toward understanding the kidney–heart link. Undetermined at this time.