Savannah Guthrie's brother asks alleged kidnapper to 'reach out'.

Camron Guthrie pleaded for whoever is holding his mother to make contact, and investigators say 84-year-old Nancy Guthrie is missing with no proof she is alive as the search continues.

Savannah Guthrie's brother Camron posted a video on Savannah's Instagram asking the person or people holding their 84-year-old mother to reach out so the family can confirm she is alive and communicate. Nancy Guthrie was reported missing after being dropped off at her Tucson, Arizona, home following a family gathering on Jan. 31. Investigators have said they have no proof Nancy is still alive and are treating the situation as a possible kidnapping. The Pima County Sheriff's Department and the FBI are involved and have said they are following leads, reviewing purported ransom communications, and using available resources to locate her. What is known: - Camron Guthrie recorded and shared a message asking whoever has their mother to make contact with the family. - The family reported Nancy missing after her doorbell camera and her pacemaker app were found disconnected in the early hours following the family visit. - Blood found on the front porch was tested and the DNA was reported as matching Nancy Guthrie. - A man in Southern California, Derrick Callella, was arrested and charged via a federal criminal complaint for transmitting a purported ransom demand; authorities said they are also investigating other alleged communications. Summary: The case has drawn broad attention and family members have made public appeals for contact from anyone holding Nancy Guthrie. Investigators said they have no proof she is alive, DNA testing results are pending and may take several days, and a federal criminal complaint has been filed in connection with at least one alleged ransom communication.