NHS alert on tibolone says 12 groups should contact their GP first

The NHS warns that tibolone is a post‑menopausal hormone treatment used to restore hormones and help prevent osteoporosis, and that it is suitable only after a year without periods (with some exceptions). The NHS also says people taking certain medicines — and some herbal remedies — should seek medical advice before starting tibolone.

The NHS has issued an alert about tibolone, a hormone treatment offered after the menopause. It says tibolone can help restore hormone levels and may be prescribed to help reduce bone thinning (osteoporosis). The NHS notes it works in a similar way to combined HRT, though some studies suggest it may raise oestrogen levels less. The alert states tibolone is normally suitable only if the last period was more than a year ago, but that it can be started immediately after removal of the ovaries or when taking gonadorelin analogues. Key points: - Tibolone is used to restore hormone levels and can be prescribed to help prevent post‑menopausal bone thinning (osteoporosis). - It acts similarly to combined HRT containing oestrogen and progestogen, though some studies suggest it may increase oestrogen less. - The drug is generally suitable only for people who have not had a period for more than a year; it may be started straight away after ovary removal or when on gonadorelin analogues. - The NHS lists certain medicines — including warfarin, phenytoin, carbamazepine and rifampicin — as examples of drugs where medical advice is recommended before using tibolone. - The guidance also highlights herbal remedies and supplements, noting many are not tested for interactions and their safety with tibolone cannot be assured. Summary: The NHS alert highlights who may be suitable for tibolone and identifies possible interactions with specific prescription medicines and some herbal products. The NHS advises checking these factors with a doctor or pharmacist before starting tibolone. Undetermined at this time.