Diet rich in vegetables may slow growth of some prostate cancers

A four-month international trial of 212 men with low‑risk prostate cancer reported slower PSA progression after a phytochemical-rich supplement, with a larger effect when a Lactobacillus probiotic was added.

A four-month trial tested whether changing the gut microbiome and increasing phytochemical-rich foods affects prostate cancer activity. Researchers enrolled 212 men with low-risk prostate cancer and gave all participants a supplement based on plant extracts; half also received a Lactobacillus probiotic. The team measured prostate-specific antigen (PSA) in blood and used MRI scans to monitor disease. Authors report slower PSA progression and higher rates of regression or stability where the probiotic was added. Key findings: - 212 men with low-risk prostate cancer took part in a four-month international trial. - All participants received a phytochemical-rich supplement; half also received a specially designed Lactobacillus probiotic. - PSA progression slowed significantly in both groups, and the change was greater in the group given the probiotic. - MRI results showed around 82% stable disease with supplement alone and about 85.5% stable disease with supplement plus probiotic, with 6.7% in the probiotic group showing regression. - Study authors say longer follow-up is planned to determine whether these changes reduce the need for major treatments. Summary: The trial reports that a supplement of plant-derived phytochemicals was associated with slower PSA progression over four months, and adding a Lactobacillus probiotic showed a larger effect. Longer-term follow-up is planned to assess whether these early changes translate into fewer major interventions or sustained benefit.