Man who died with dementia at 24 leaves his brain to science

Andre Yarham was diagnosed with frontotemporal dementia in his early twenties and died on 27 December; his brain has been donated to Addenbrooke's Hospital for research.

Andre Yarham of Dereham, Norfolk first saw doctors at age 22 after his mother noticed increasing forgetfulness and changes in his behaviour. Scans showed unusual brain shrinkage and he was diagnosed at Addenbrooke's Hospital with frontotemporal dementia linked to a protein mutation. His needs became difficult for his family to manage and he moved into a care home; his condition progressed and he lost his speech in the month before he died. He died on 27 December at age 24, and his brain has been donated to Addenbrooke's Hospital for research. Key facts: - He first sought medical help at 22 after family noticed forgetfulness and inappropriate behaviour. - Scans and specialist review led to a diagnosis of frontotemporal dementia, which the article reports was linked to a protein mutation. - His care needs increased over months; he entered a care home, later used a wheelchair, and lost his speech before dying. - He died on 27 December and his brain has been donated to Addenbrooke's Hospital for research. Summary: The family has spoken publicly to highlight that dementia can affect younger adults, and his mother said she hoped the donation might benefit other families in the future. The donated brain will be used for research at Addenbrooke's Hospital.