Colorectal cancer: over 150,000 new diagnoses expected in 2026

The American Cancer Society estimates more than 150,000 new colorectal cancer cases in the U.S. in 2026, and rates are increasing among adults under 50.

Experts say the American Cancer Society estimates there will be more than 150,000 new colorectal cancer cases in the U.S. in 2026. Rates have risen in adults younger than 50 in recent years, and clinicians point to delayed diagnosis as a key contributor. The recent death of actor James Van Der Beek, diagnosed in 2023, has brought additional public attention to the disease. Medical groups and researchers continue to discuss screening age and risk-based approaches. Key facts: - The American Cancer Society projects about 108,860 new colon cancer cases and about 49,990 new rectal cancer cases in 2026. - Reported rates among Americans under 50 increased by about 2.9% per year from 2013 to 2022; rates for those aged 50–64 rose by about 0.4% per year in the same period. - Screening guidelines were lowered from age 50 to 45 in 2021, and experts are debating further changes versus risk-based evaluation when symptoms or family history are present. Summary: The projected case numbers and rising rates among younger adults indicate a shifting pattern in disease burden. Discussion among clinicians and researchers about screening approaches is ongoing, and any next policy or guideline changes are undetermined at this time.