Business

Roche has partnered with C4 Therapeutics to develop degrader-antibody conjugates for cancer, with Roche obtaining exclusive rights to selected targets and a deal that includes a US$20 million upfront payment and more than US$1 billion in potential milestones and tiered royalties.

At the HumanX conference, industry leaders urged workers to emphasize human skills even as multiple companies cite AI when announcing layoffs; the precise scale of job losses tied to AI remains undetermined.

The Small Business Administration will provide low-interest disaster loans to Colorado small businesses, small agricultural cooperatives, nurseries and private nonprofits with losses tied to drought beginning Nov. 1, 2025; loans can reach $2 million and applications are due by Dec. 7.

Authorities say a grand jury indicted eight people and that five were charged with second-degree murder after a July explosion at an illegal fireworks factory that killed seven. Former Yolo County Lt. Sam Machado and company founder Kenneth Chee were arrested, and arraignments for five booked defendants are scheduled Monday.

A U.S. homeowner posted on Reddit defending heat pumps, saying they are energy-efficient and describing a year-old Mitsubishi Hyper Heat installation; the post noted that rising utility rates can reduce expected savings and that pairing heat pumps with solar reshaped their bill.

The article ranks 2026 model-year pickups by manufacturer advertised starting MSRP and highlights affordable options from compact hybrids like the Ford Maverick to midsize and full-size pickups such as the Toyota Tacoma and Ford F-150.

Conservative leader Pierre Poilievre called on the federal government to clarify that fee-simple private property takes priority over other claims and to ensure future agreements with First Nations explicitly protect private-property rights, citing a recent B.C. court ruling and a federal agreement with the Musqueam First Nation as context.

Some tribally owned stations are selling gasoline at lower prices than nearby non-tribal stations because state fuel taxes generally do not apply on tribal land, and nationwide prices have risen since the Iran war began.

The article reports CoreWeave expanded a long-term agreement to supply Meta with AI cloud capacity through December 2032 worth about US$21 billion, and that the company also announced related financings and a multi-year Anthropic cloud deal.

CanLit Responds says its boycott of the Giller Prize is over after receiving confirmation that the prize no longer has sponsorship ties to Scotiabank, Indigo Books and the Azrieli Foundation; the Giller Foundation did not respond to requests for comment.

Discover Puerto Rico says the island welcomed 8.1 million visitors in 2025, up 8% from the year before, and the tourism bureau is promoting an "Awaken Your Senses" campaign that directs visitors beyond San Juan toward regions such as Vieques, the east, the central mountains, Cabo Rojo and the south.

Ottawa has doubled funding and voted to double the build rate of supportive housing to address a wait list of about 450 people for 350 units; a new advisory body of health and housing partners was launched to better coordinate services.

An ATTOM report found property taxes rose in 40 states and the District of Columbia last year, while $396.8 billion was levied on 89.6 million single-family homes and the average tax bill was $4,427.

Medline launched Pick Pack Pro at its Montgomery, New York distribution center on April 6; the system combines robotic sortation, conveyors and automated packing to send medical supplies to health plan members' homes and is slated for wider rollout across 45 U.S. distribution centers.

The family of 17-year-old Larissa Rodriguez filed a wrongful death suit saying a Hidalgo County medical examiner ruled her cause of death was an enlarged heart tied to stress and large amounts of caffeine. The suit names beverage distributors and seeks more than $1 million in Hidalgo County District Court.

Officials announced a preliminary agreement with BNSF for the Colorado Front Range Passenger Rail, and planners say a starter Northwest Corridor service of three round trips is planned with an estimated $333 million launch cost and a target to begin service by 2029.

Disney plans to cut about 1,000 jobs, mainly in its marketing division, under CEO Josh D'Amaro as part of 'Project Imagine'. Undetermined at this time.

The Saskatchewan Realtors Association reports the residential benchmark price is $374,100, about six percent higher than a year earlier; Regina’s benchmark reached a record $343,700 in March, and Regina and Saskatoon each have roughly 1.6 months of supply.

Ceasefire talks in Pakistan involve the United States and Iran amid deep mutual distrust; reopening the Strait of Hormuz has become a central sticking point.

Chevrolet says the newly revealed Grand Sport will be the last major variant of the mid‑engine C8 Corvette, and the company will continue refining the model while sources report work on a next‑generation C9 is underway.

The Dow gained about 1,342 points while U.S. and international oil benchmarks fell below $100 a barrel after a temporary ceasefire in the Iran war eased concerns about disruptions in the Strait of Hormuz.

The tax changes increased average refunds this season and the White House has promoted gains for tips, overtime and Social Security; analyses project about 60% of the law’s tax savings will go to the top fifth of households, while some workers face caps or exclusions.

Moss is a low‑maintenance groundcover that often thrives in shade and acidic, compact soils; successful planting typically involves preparing the soil, selecting suitable moss varieties, and watering daily for about four to six weeks until established.

The Writers Guild of America published a memorandum for a four-year contract with the AMPTP that the guild says would restore health-plan sustainability and deliver an estimated $280 million in studio contributions; the deal also includes minimum pay increases and new AI information provisions and will go to members for ratification.

Jim Whittaker, who became the first American to reach the summit of Mount Everest on May 1, 1963, has died at 97; he later served as a manager and CEO at the outdoor co-op REI.

Saskatchewan officials say crews have trained, prevention work is underway and equipment and aircraft are being readied as they prepare for a summer that could bring hot, windy conditions; independent reviews of last year’s response are nearing completion.

Toyota Center and Clutch City Sports & Entertainment announced a $180 million overhaul called "Toyota Center Reimagined," with construction set to begin after the 2025–26 Rockets season and completion expected by fall 2027; the team says owner Tilman Fertitta will cover close to half the cost.

CoBank's quarterly report says rising fuel and energy costs are likely to weigh more heavily on rural America because of longer driving distances and diesel-dependent industries, and that higher energy costs could boost headline inflation by about 1% in the coming months.

An opinion argues that rechartering the Federal Home Loan Bank System, created in 1932, could redirect funding to so-called 'missing middle' multifamily housing and is estimated to spur about 200,000 new homes a year, including roughly 40,000 below-market units.

A Social Security rule lets retirees who delay claiming until after full retirement age request up to six months of back pay as a lump sum; accepting it reduces future monthly payments because delayed retirement credits are forfeited.