Oprah Winfrey says weight loss gave her new freedom

Oprah Winfrey discussed her new book Enough and described how recent weight loss and lifestyle changes gave her a sense of freedom; her co-author Dr. Ania M. Jastreboff also spoke about how GLP-1s work during a Jan. 13, 2026 interview on TODAY.

Oprah Winfrey appeared on TODAY with Jenna Bush Hager and Sheinelle Jones to discuss her new book Enough: Your Health, Your Weight, and What It's Like to Be Free. She described recent weight loss, the lifestyle changes she experienced, and said the journey gave her a new sense of freedom. Winfrey also said that learning obesity is not the fault of people who live with it proved a belief held by her father to be incorrect. Her co-author, Dr. Ania M. Jastreboff, an endocrinologist and associate professor at the Yale School of Medicine, joined the conversation to explain how GLP-1s work. Key points: - Oprah discussed her book Enough and described lifestyle changes connected to her weight loss. - She said the weight-loss experience gave her a new sense of freedom. - Winfrey said learning that obesity is not the fault of people who live with it contradicted her father's view. - Dr. Ania M. Jastreboff, her co-author and a Yale endocrinologist, explained how GLP-1s work during the interview. - The conversation aired on TODAY on Jan. 13, 2026. Summary: The interview combined Winfrey's personal account with medical context from her co-author, focusing on how weight loss affected her sense of freedom and on broader conversations about obesity and treatments. Undetermined at this time.