Anemia linked to a 66% higher risk of dementia in a Swedish study

A Swedish study found that people with anemia had a 66% higher likelihood of developing dementia and that anemia was associated with Alzheimer’s-related blood markers such as p‑tau217; researchers say more study is needed.

A Swedish research team reported an association between anemia and later dementia in older adults. The study found that participants with anemia had a 66% higher likelihood of developing dementia than those with normal hemoglobin. Researchers also observed links between anemia and blood markers tied to Alzheimer’s disease, including phosphorylated tau 217 (p‑tau217). Study authors and outside specialists said further research is needed to determine whether treating anemia would change dementia risk. Key findings: - Participants with anemia had a 66% higher likelihood of developing dementia compared with those with normal hemoglobin. - Anemia was associated with higher levels of Alzheimer’s-related blood biomarkers, including phosphorylated tau 217 (p‑tau217). - The highest observed dementia risk occurred among people who had both anemia and elevated Alzheimer’s biomarkers. - The average age of study participants was 72, and the authors noted that additional research is required to clarify cause and effect and to test whether treatment alters risk. Summary: The study suggests a notable association between anemia and later dementia and identifies a possible link with Alzheimer’s biomarkers, but it does not establish that anemia causes dementia or that treating anemia will reduce risk. Further research was recommended. Undetermined at this time.